Table 3 Proteins in human serum after 6 h of sleep deprivation identified by iTRAQ analysis
From: Human blood serum proteome changes after 6 hours of sleep deprivation at night
Swissprot ID | Protein Short Name | Protein Name | P-value | Average foldchange |
|---|---|---|---|---|
Up-regulated proteins (14) | ||||
 Q9HBW9 | ELTD1 | EGF latrophilin and seven transmembrane domain-containing protein 1 | 0,0002 | 1064 |
 P62805 | H4 | Histone H4 | 0,0067 | 2291 |
 P07951 | TPM2 | Tropomyosin beta chain | 0,0082 | 1153 |
 P0CG38 | POTEI | POTE ankyrin domain family member I | 0,0088 | 1035 |
 P23141 | EST1 | Liver carboxylesterase 1 | 0,0102 | 1075 |
 Q6ZMR3 | LDH6A | L-lactate dehydrogenase A-like 6A | 0,0143 | 1,11 |
 P06703 | S10A6 | Protein S100-A6 | 0,0145 | 1525 |
 P01880 | IGHD | Ig delta chain C region | 0,0247 | 1184 |
 Q86T29 | ZN605 | Zinc finger protein 605 | 0,0438 | 1059 |
 A5A3E0 | POTEF | POTE ankyrin domain family member F | 0,0441 | 1036 |
 P13716 | HEM2 | Delta-aminolevulinic acid dehydratase | 0,0454 | 1115 |
 P33151 | CADH5 | Cadherin-5 | 0,0454 | 1074 |
 P02144 | MYG | Myoglobin | 0,0476 | 1094 |
 P55285 | CADH6 | Cadherin-6 | 0,0499 | 1036 |
Down-regulated proteins (20) | ||||
 P05155 | IC1 | Plasma protease C1 inhibitor | 0,0023 | − 1129 |
 P00390 | GSHR | Glutathione reductase, mitochondrial | 0,0029 | − 1068 |
 P23470 | PTPRG | Receptor-type tyrosine-protein phosphatase gamma | 0,0036 | − 1058 |
 O75022 | LIRB3 | Leukocyte immunoglobulin-like receptor subfamily B member 3 | 0,0048 | − 1101 |
 P00736 | C1R | Complement C1r subcomponent | 0,006 | − 1047 |
 Q8TDY8 | IGDC4 | Immunoglobulin superfamily DCC subclass member 4 | 0,0134 | − 1065 |
 Q10588 | BST1 | ADP-ribosyl cyclase 2 | 0,0169 | − 1066 |
 P08709 | FA7 | Coagulation factor VII | 0,0186 | −1,05 |
 P07942 | LAMB1 | Laminin subunit beta − 1 | 0,0188 | − 1022 |
 P08294 | SODE | Extracellular superoxide dismutase [Cu-Zn] | 0,0199 | −1,05 |
 Q9UHG3 | PCYOX | Prenylcysteine oxidase 1 | 0,0208 | − 1067 |
 O75326 | SEM7A | Semaphorin-7A | 0,0212 | − 1057 |
 P35542 | SAA4 | Blood serum amyloid A-4 protein | 0,0223 | −1058 |
 Q86VB7 | C163A | Scavenger receptor cysteine-rich type 1 protein M130 | 0,0357 | − 1063 |
 P23142 | FBLN1 | Fibulin − 1 | 0,036 | − 1038 |
 P48740 | MASP1 | Mannan-binding lectin serine protease 1 | 0,0387 | − 1073 |
 Q8N3C0 | ASCC3 | Activating signal cointegrator 1 complex subunit 3 | 0,0414 | -1105 |
 P24387 | CRHBP | Corticotropin-releasing factor-binding protein | 0,0417 | -1066 |
 P58215 | LOXL3 | Lysyl oxidase homolog 3 | 0,0457 | -1084 |
 O75882 | ATRN | Attractin | 0,0469 | -1039 |