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Table 1 Descriptive Means ± standard deviations and proportions (%) above clinical cut-off score, of the ESS score, ISI score, PhQ-4 score, VAS sleepiness, and Digit Vigilance Test

From: Hyperactivity in patients with narcolepsy and idiopathic hypersomnia: an exploratory study

Variable

[1]

IH

(n = 5)

[2]

Narcolepsy

(n = 7)

[3]

Total patients

(n = 12)

[4]

Control

(n = 12)

[1,2,4]

Test-statistic

p-value

[3,4]

Test-statistic

p-value

[1,2]

Test-statistic

p-value

ESS total score

14.2 ± 4.8

11.9 ± 3.6

12.8 ± 4.1

4.8 ± 3.3

(H = 2, N = 24) = 15.1

0.0005

 < 0.005$

n.s.$

ESS cut-off > 10

80%

57.1%

66.7%

0%

ML Chi-square (2) = 16.0

0.001

0.0003£

n.s.£

ISI total score

11 ± 4.6

11.6 ± 5.6

11.3 ± 5

3.2 ± 2.6

(H = 2, N = 24) = 14.5

0.0007

 < 0.005$

n.s.$

ISI cut-off ≥ 8

60%

85.7%

75%

8.3%

ML Chi-square (2) = 13.3

0.001

0.003£

n.s.£

PhQ-4 total score

3.4 ± 3.8

3.1 ± 3.6

3.3 ± 3.5

0.6 ± 0.8

(H = 2, N = 24) = 4.2

0.124

n.s.$

n.s.$

PhQ-4 clinical cut-off ≥ 3

60%

42.9%

50%

0%

ML Chi-square (2) = 10.7

0.005

0.014£

n.s.£

VAS Sleepiness 20-min

6.5 ± 2.7

5.5 ± 3.0

5.9 ± 2.8

2.5 ± 2.0

(H = 2, N = 24) = 8.1

0.017

 < 0.05$

n.s.$

VAS Sleepiness 40-min

8.0 ± 2.7

8.1 ± 2.3

8.0 ± 2.4

3.1 ± 2.4

(H = 2, N = 24) = 11.7

0.003

 < 0 .005$

n.s.$

VAS Sleepiness 60-min

7.9 ± 3.1

8.4 ± 2.3

8.2 ± 2.5

4.1 ± 3.5

(H = 2, N = 24) = 9.4

0.009

 < 0 .01$

n.s.$

DVT Red time (sec)

256.0 ± 131.3

168.4 ± 26.4

205 ± 93.3

198.7 ± 33.6

(H = 2, N = 24) = 6.0

n.s.

n.s.$

n.s.$

DVT Red Total errors

1.0 ± 1.2

2.4 ± 2.1

1.8 ± 1.9

1.4 ± 1.4

(H = 2, N = 24) = 1.9

n.s.

n.s.$

n.s.$

DVT Blue time (sec)

250.6 ± 133.7

174.0 ± 27.6

205.9 ± 92.0

199.6 ± 37.4

(H = 2, N = 24) = 3.3

n.s.

n.s.$

n.s.$

DVT Blue Total errors

3.2 ± 2.6

2.4 ± 4.0

2.8 ± 3.3

3.5 ± 3.2

(H = 2, N = 24) = 1.5

n.s.

n.s.$

n.s.$

DVT total time

507.2 ± 264.5

342.4 ± 53.3

411.1 ± 184.9

398.0 ± 70.7

(H = 2, N = 24) = 4.5

n.s.

n.s.$

n.s.$

DVT Total errors

4.2 ± 2.6

4.9 ± 5.1

4.6 ± 4.1

4.8 ± 3.9

(H = 2, N = 4) = 0.15

n.s.

n.s.$

n.s.$

  1. Bold are significant results at p < 0.05. Percentages represent the number of subjects above the clinical cut-off of all questionnaires
  2. DVT Digit Vigilance Test; ESS Epworth Sleepiness Scale (cut-off > 10); IH Idiopathic Hypersomnia, ISI Insomnia Severity Index (cut-off ≥ 8), H Kruskal–Wallis ANOVA by ranks; ML Chi-square[degrees of freedom = (2)] Maximum Likelihood Chi-square; PhQ-4 Patient Health Questionnaire for Depression and Anxiety (cut-off ≥ 3); VAS Visual Analogue Scale
  3. £Fisher exact
  4. $Kolmogorov–Smirnov Test