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Table 1 Phenotype Definitions

From: Distinct polysomnographic and ECG-spectrographic phenotypes embedded within obstructive sleep apnea

Phenotype

Phenotype criteria

Polysomnogram chemoreflex

Central apnea index ≥ 5/h of sleep

Spectrogram chemoreflex

Presence of narrow band elevated low frequency coupling

Polysomnogram fragmentation—SE

Sleep efficiency ≤ 70% total sleep time

Polysomnogram fragmentation—N1

NREM N1 ≥ 30% total sleep time

Polysomnogram fragmentation—WASO

Wake after sleep onset ≥ 60 min

Spectrogram fragmentation

High frequency coupling ≤ 30% total sleep time

Polysomnogram consolidation—SE

Sleep efficiency ≥ 90% total sleep time

Polysomnogram consolidation—N1

NREM N1 ≤ 10% total sleep time

Polysomnogram consolidation—WASO

Wake after sleep onset ≤ 30 min

Spectrogram consolidation

High frequency coupling ≥ 50% total sleep time

  1. SE sleep efficiency; N1 NREM stage 1; WASO wake after sleep onset