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Table 5 Polysomnographic and spectrographic metrics across apnea severity groups (mean ± SD)

From: Distinct polysomnographic and ECG-spectrographic phenotypes embedded within obstructive sleep apnea

Polysomnographic variable Mild (n = 70) Moderate (n = 394) Severe (n = 320) Extreme (n = 188)
 Total Sleep Time (minutes) 386 ± 68 376 ± 64 388 ± 63 368 ± 74
 Sleep efficiency % TST 80.9 ± 13.3 79 ± 12.8 80.1 ± 11.1 76.4 ± 14.2
 Arousal index/hour of sleep 14.2 ± 10.4 19.8 ± 12.1 29 ± 15.3 53.9 ± 28.6
 S1 % TST 11.4 ± 7.9 14 ± 8.4 18.1 ± 11.2 30.6 ± 22.5
 S2 % TST 63.6 ± 8.4 62.6 ± 9.7 60.6 ± 11 53.7 ± 20.9
 S3 + S4 % TST 5.5 ± 7.2 4 ± 6.7 3 ± 5.4 1.7 ± 4.3
 REM % TST 19.4 ± 6.6 19.2 ± 6.5 18.2 ± 6.8 13.9 ± 7.2
 RDI/hour of sleep 5.5 ± 2.7 19.1 ± 5.8 44 ± 8.7 83.6 ± 17.6
 CAI/hour of sleep 0.8 ± 0.2 0.3 ± 1 1.2 ± 3 3.2 ± 9.3
 Minimum SaO2 87.7 ± 11.5 84.8 ± 5.1 79.7 ± 7.5 72.7 ± 10.6
ECG-spectrographic variable n = 54 n = 296 n = 209 n = 112
 HFC % TST 50.8 ± 19.6 44.5 ± 21 36.9 ± 20.8 22.1 ± 19.7
 LFC % TST 29.4 ± 13.8 35.7 ± 16.2 45.6 ± 17.8 62.8 ± 21
 e-LFC % TST 11.1 ± 10.1 15.3 ± 11.5 22.3 ± 16.2 37.3 ± 25.2
 e-LFCNB % TST 0.02 ± 0.07 1.2 ± 2.7 3.8 ± 8.5 9.9 ± 13.3
 VLFC % TST 17.6 ± 7.1 17.6 ± 7.4 15.2 ± 6.9 12.9 ± 6.9
  1. WASO wake after sleep onset; N1 stage 1 NREM sleep; CAI central apnea index; S2-S4 pre-2007 NREM sleep stages; HFC high frequency coupling; REM rapid eye movement; LFC low frequency coupling; VLFC very low frequency coupling; e-LCF elevated-low frequency coupling; e-LFC NB narrow band e-LFC