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Table 7 NREM vs. REM dominance: clinical and polysomnographic features

From: Distinct polysomnographic and ECG-spectrographic phenotypes embedded within obstructive sleep apnea

Demographics and Polysomnogram Metrics

NREM dominant (242)

REM dominant (429)

p

Age (years)

51.2 ± 13.9

49.6 ± 11.9

0.11

Gender (male %)

80.2

55.7

<0.001 (Chi2)

Race (white, %)

74.8

69.9

0.10

Body Mass Index Kg/M2

30.6 ± 6.7

31.3 ± 7.3

0.25

Total sleep time (TST)

282.8 ± 64

386.4 ± 58.1

0.46

Sleep efficiency % TST

79.2 ± 12.2

80.7 ± 11.1

0.10

S1 % TST

21.7 ± 16.8

14.9 ± 10.1

<0.001

S2 % TST

58.3 ± 15.5

62.3 ± 9.8

<0.001

S3+ S4 % TST

2.1 ± 3.8

3.1 ± 5.3

0.005

REM

17.1 ± 6.7

18.9 ± 6.7

0.002

Arousal Index/hour of sleep

36.5 ± 26.1

22.6 ± 15.1

<0.001

RDI/hour of sleep

49.9 ± 29.9

28.8 ± 20.1

<0.001

Obstructive apnea index/hour of sleep

25 ± 15.4

9.6 ± 13.7

<0.001

Central apnea index/hour of sleep

2 ± 7.2

0.5 ± 2.1

<0.001

Mixed apnea index/hour of sleep

3 ± 7.4

0.4 ± 1.5

<0.001

Hypopnea index/hour of sleep

19.9 ± 14.5

18.3 ± 11.9

0.11

RDI-NREM/hour of sleep

52.9 ± 30.5

24.7 ± 20.3

<0.001

RDI-REM/hour of sleep

34.5 ± 25.3

46.5 ± 25.3

<0.001

Oxygen desaturation index/hour of sleep

34 ± 29.6

16.4 ± 17.2

<0.001

Minimum saturation

79.5 ± 10.3

82.9 ± 6.8

<0.001

Time less than 85% saturation (minutes)

4.8 ± 11.5

1 ± 2.6

<0.001

PLM/hour of sleep

5.8 ± 12.5

6.2 ± 16.2

0.77

  1. All values mean and standard deviation, unless other specified
  2. S1-S4 Pre-2007 NREM sleep stages; RDI respiratory disturbance index; REM rapid eye movement NREM: non-rapid eye movement; PLM periodic limb movement