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Table 7 NREM vs. REM dominance: clinical and polysomnographic features

From: Distinct polysomnographic and ECG-spectrographic phenotypes embedded within obstructive sleep apnea

Demographics and Polysomnogram Metrics NREM dominant (242) REM dominant (429) p
Age (years) 51.2 ± 13.9 49.6 ± 11.9 0.11
Gender (male %) 80.2 55.7 <0.001 (Chi2)
Race (white, %) 74.8 69.9 0.10
Body Mass Index Kg/M2 30.6 ± 6.7 31.3 ± 7.3 0.25
Total sleep time (TST) 282.8 ± 64 386.4 ± 58.1 0.46
Sleep efficiency % TST 79.2 ± 12.2 80.7 ± 11.1 0.10
S1 % TST 21.7 ± 16.8 14.9 ± 10.1 <0.001
S2 % TST 58.3 ± 15.5 62.3 ± 9.8 <0.001
S3+ S4 % TST 2.1 ± 3.8 3.1 ± 5.3 0.005
REM 17.1 ± 6.7 18.9 ± 6.7 0.002
Arousal Index/hour of sleep 36.5 ± 26.1 22.6 ± 15.1 <0.001
RDI/hour of sleep 49.9 ± 29.9 28.8 ± 20.1 <0.001
Obstructive apnea index/hour of sleep 25 ± 15.4 9.6 ± 13.7 <0.001
Central apnea index/hour of sleep 2 ± 7.2 0.5 ± 2.1 <0.001
Mixed apnea index/hour of sleep 3 ± 7.4 0.4 ± 1.5 <0.001
Hypopnea index/hour of sleep 19.9 ± 14.5 18.3 ± 11.9 0.11
RDI-NREM/hour of sleep 52.9 ± 30.5 24.7 ± 20.3 <0.001
RDI-REM/hour of sleep 34.5 ± 25.3 46.5 ± 25.3 <0.001
Oxygen desaturation index/hour of sleep 34 ± 29.6 16.4 ± 17.2 <0.001
Minimum saturation 79.5 ± 10.3 82.9 ± 6.8 <0.001
Time less than 85% saturation (minutes) 4.8 ± 11.5 1 ± 2.6 <0.001
PLM/hour of sleep 5.8 ± 12.5 6.2 ± 16.2 0.77
  1. All values mean and standard deviation, unless other specified
  2. S1-S4 Pre-2007 NREM sleep stages; RDI respiratory disturbance index; REM rapid eye movement NREM: non-rapid eye movement; PLM periodic limb movement