Author, year | Study type | Definition of REM rebound | Number | Age, years | BMI, Kg/m2 | Pre-CPAP REM % | Post-CPAP REM% | MD (95% CI) | P-value |
---|---|---|---|---|---|---|---|---|---|
Brillante et al. 2012 | Retrospective | 20% or more increase in % REM sleep on titration night when compared to baseline PSG | 335 | 54.0 ± 13.9 | 33.3 ± 7.3 | 16.9 ± 7.8 | 18.4 ± 8.8 | 1.5 (2.762, 0.238) | 0.0199 |
Koo et al. 2012 | Retrospective | At least one REM period of >/30 min duration in the treatment portion AND an increase in REM in the treatment portion of >/20% | 95 | 56.7 ± 11.1 | 35.0 ± 7.0 | 6.7 ± 9.3 | 23.3 ± 15.1 | 16.5 (12.911, 20.089) | 0.0001 |
Kushida et al. 2011 | Prospective Randomized, controlled trial | - | 57 | 48.8 ± 12 | 34.9 ± 8.0 | 13.1 ± 9.0 | 22.8 ± 8.4 | 9.7 (6.469, 12.931) | 0.0001 |
Yaegashi et al. 2009 | Retrospective | - | 280 | 58.6 ± 14.7 | 25.7 ± 3.9 | 13.1 ± 6.2 | 18.1 ± 7.0 | 5.0 (3.902, 6.098) | 0.0001 |
Osuna et al. 2008 | Retrospective | 6% or more increase in % REM sleep on titration night when compared to baseline PSG | 179 (118 M + 61 F) | 48.6 ± 4 (M) 51.6 ± 12.9 (F)c | 33.7 ± 7.7 (M) 39.2 ± 8.2 (F)c | 15.55 | 21.57 | - | - |
Drake et al. 2003 | Prospective | - | 71 | 50.7 ± 10.6 | - | 12.8 ± 5.6 | 19.1 ± 8.9 | 6.3 (3.833, 8.767) | 0.0001 |
Verma et al. 2001 | Retrospective | - | 44 | 51.6 | 12.1 ± 8.3a 12.7 ± 9.0b | 17.2 ± 8.1a 15.6 ± 8.6b | 5.1 (1.624,8.576) 2.9 (−0.831, 6.631) | 0.0045 0.1259 | |
Randerath et al. 2001 | Prospective | - | 25 | 52.8 ± 9.0 | 31.4 ± 5.0 | 14.2 ± 6.7 | 17.1 ± 7.4 | 2.9 (−1.114, 6.914) | 0.1529 |
Parrino et al. 2000 | Retrospective | - | 10 | 47.4 ± 5.3 | >36 | 81 ± 30d | 149 ± 32d | 68 (38.86, 97.14) | 0.0001 |
Collard et al. 1996 | Prospective | - | 80 | 52.1 ± 10.6 | 33.4 ± 6.6 | 17.8 ± 6.9 | 21.9 ± 9.5 | 4.1 (1.507, 6.693) | 0.0021 |
Yamashiro and Kryger 1995 | Prospective | - | 107 | 52.3 ± 12.1 | 34.4 ± 8.2 | 11.2 ± 9.5 | 25.3 ± 14.4 | 14.1 (10.812, 17.388) | 0.0001 |
Lamphere et al. 1989 | Prospective | - | 13 | 50.1 ± 11.6e | 35.6 ± 9.5 | 9.2 ± 6.4 | 20.4 ± 8.7 | 11.2 (5.018, 17.382) | 0.0010 |
Aldrich et al. 1989 | Prospective | - | 26 | 47 | - | 43.1 ± 5.4d | 73.3 ± 6.9d | 30.2 (26.749, 33.651) | 0.0001 |
Issa and Sullivan 1986 | Prospective | - | 12 | 47.4 | 18.4 ± 2.0 | 30.6 ± 2.0 | 12.2 (10.507, 13.893) | 0.0001 | |
Combined Means | 53.65 ± 12.60 | 34.58 ± 11.20 | 13.82 ± 8.17 | 19.99 ± 10.06 | 6.17 (5.408, 6.931) | 0.0001 | |||
1252 | 1171 | 1119 | 1119 |