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Table 2 REM rebound on CPAP titration: PSG parameters

From: Rapid Eye Movement (REM) rebound on initial exposure to CPAP therapy: a systematic review and meta-analysis

Study, year Baseline AHI % of patients with REM rebound Titration (T) or Split night (SN) study
Brillante et al. 2012 40.7 ± 26.1 23% T
Koo et al. 2012 44.5 ± 28.8 37% SN
Kushida et al. 2011 41.1 ± 31.6 - T
Yaegashi et al. 2009 48.5 ± 20.2 - T
Osuna et al. 2008 >10a 46% T
Drake et al. 2003 62.0 ± 32.2 - T
Verma et al. 2001 RDI >10a - T
Randerath et al. 2001 32.2 ± 18.1 - Tc
Parrino et al. 2000 67.9 - T
Collard et al. 1996 24.2 ± 18.8 - T
Yamashiro and Kryger 1995 23.6 ± 26.3 - SNb
Lamphere et al. 1989 72.9 ± 21.5 - T
Aldrich et al. 1989 69.6 ± 5.9   T
Issa and Sullivan 1986 57.6 - T
  1. aDenotes AHI cut off criteria for entry into the study, not the mean AHI
  2. bDenotes that this study reported data from both Split night study as well as titration night study, but data tabulated represents Split night values as this was the study with first exposure to CPAP occurred and first REM rebound was witnessed
  3. cDenotes PSG data collected from fixed CPAP setting, obtained using a manual CPAP titration 1–2 days prior