|
Study, year
|
Baseline AHI
|
% of patients with REM rebound
|
Titration (T) or Split night (SN) study
|
|---|
|
Brillante et al. 2012
|
40.7 ± 26.1
|
23%
|
T
|
|
Koo et al. 2012
|
44.5 ± 28.8
|
37%
|
SN
|
|
Kushida et al. 2011
|
41.1 ± 31.6
|
-
|
T
|
|
Yaegashi et al. 2009
|
48.5 ± 20.2
|
-
|
T
|
|
Osuna et al. 2008
|
>10a
|
46%
|
T
|
|
Drake et al. 2003
|
62.0 ± 32.2
|
-
|
T
|
|
Verma et al. 2001
|
RDI >10a
|
-
|
T
|
|
Randerath et al. 2001
|
32.2 ± 18.1
|
-
|
Tc
|
|
Parrino et al. 2000
|
67.9
|
-
|
T
|
|
Collard et al. 1996
|
24.2 ± 18.8
|
-
|
T
|
|
Yamashiro and Kryger 1995
|
23.6 ± 26.3
|
-
|
SNb
|
|
Lamphere et al. 1989
|
72.9 ± 21.5
|
-
|
T
|
|
Aldrich et al. 1989
|
69.6 ± 5.9
| |
T
|
|
Issa and Sullivan 1986
|
57.6
|
-
|
T
|
-
aDenotes AHI cut off criteria for entry into the study, not the mean AHI
-
bDenotes that this study reported data from both Split night study as well as titration night study, but data tabulated represents Split night values as this was the study with first exposure to CPAP occurred and first REM rebound was witnessed
-
cDenotes PSG data collected from fixed CPAP setting, obtained using a manual CPAP titration 1–2 days prior
