Table 1 Medications Not Classified As Sedative/Hypnotics Inducing Daytime Sleepiness As A Side Effect
Medication Class | Neurochemical Basis For Sleepiness |
|---|---|
Antiparkinsonian Agents | Dopamine Receptor Agonists |
Antimuscarinic/ Antispasmodic | Varied effects |
Skeletal Muscle Relaxants | Varied Effects |
Alpha- Adrenergic Blocking Agents | Alpha-1 Adrenergic Antagonists |
Beta-Adrenergic Blocking Agents | Beta Adrenergic Antagonists |
Gamma-Hydroxy-Butyrate | GABA Agonist |
Opiate Agonists | Opioid Receptor Agonists (General Cns Depression) |
Opiate Partial Agonists | Opioid Receptor Agonists (General Cns Depression) |
Anticonvulsants | |
Barbiturates | GABA Agonist |
–Benzodiazepines | GABA Agonist |
- Hydantoins | Neurotransmitter effect poorly defined - electrophysiolic? |
- Succinimides | Neurotransmitter effect poorly defined - electrophysiolic? |
Other Antidepressants | |
- Maoi | Norepinephrine, 5ht & Dopamine |
- Ssri | Serotonin Uptake Inhibition |
-Agents With Mixed Effects | Serotonin, Dopamine, & Norepinephrine |
Other Antipsychotics | Dopamine Receptor Blockage, Varied Effects On Histaminic, Cholinergic And Alpha Adrenergic Receptors |
Other Benzodiazepines Not Used For Sedation | GABA Agonist |
Anxiolytics, misc. Sedative & hypnotics | GABA Agonist, Varied Effects |
Antitussives | Neurotransmitter Effect Poorly Defined |
Antidiarrhea agents | Neurotransmitter Effect Poorly Defined - Opioid In Some Cases |
Antiemetics | Antihistamine & Varied Effects |
Genitourinary Smooth Muscle Relaxants | Neurotransmitter Effect Poorly Defined |