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Table 2 Consistent quantitative alteration in physiologic EEG frequencies induced by psychoactive medications

From: Treating insomnia with medications

Class of drugs Eeg frequencies Treatment indications
Delta (0.5–1.5 Hz) Theta (5.5–8.5 Hz) Alpha (8.5–11 Hz) Sigma (12–16 Hz) Beta/Gamma (21–32 Hz)  
Benzodiazepines (BZDs)    Decrease Increase Increase Anxiety
Sedation
Barbiturates     Increase Increase Anxiety
Sedation
Epilepsy
Tricyclic Antidepressants (TCAs) decrease Decrease    Increase Depression
SSRI Antidepressants decrease   Increase    Depression
Anxiety
OCD
Amphetamines decrease Decrease    increase Somnolence
Narcolepsy
AD/HD
Opiates increase   decrease    Pain
Anticonvulsants
Phenytoin, valproate, carbamazepine
  increase     Epilepsy
Gamma hydroxy butyrate (GHB) increase      Cataplexy
Narcolepsy
Classic Neuroleptics   increase decrease decrease   Schizophrenia
Psychosis