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Table 1 Major underlying diseases of abnormal behaviors during sleep (ABDS)

From: Abnormal behaviors during sleep from the viewpoint of sleep epileptology: current and future perspectives on diagnosis

Disease categories

Representative ABDS

Sleep disordersa

 Insomnia

movements associated with sleep arousals

 Sleep-related breathing disorders

occasional flailing movements associated with apneic arousals

 Central disorders of hypersomnolence

narcolepsy with “negative” and “active” movement abnormalities

 Parasomnias

NREM/REM parasomnias, status dissociatus

 Sleep-related movement disorders

restless legs syndrome, periodic limb movement disorder, sleep-related leg cramp, sleep-related bruxism, fasciomandibular myoclonus, sleep-related rhythmic movement disorder, benign sleep myoclonus of infancy, propriospinal myoclonus at sleep onset

 Sleep-related medical and neurological disorders

sleep-related epilepsy

 Other sleep disorders

anti-IgLON5 disease, ADCY5-associated disease, benign nocturnal alternating hemiplegia of childhood

 Isolated symptoms or normal variants

excessive fragmentary myoclonus, hypnagogic foot tremor, alternating leg muscle activation, high frequency leg movements, hypnic jerk, neck myoclonus during sleep

Psychiatric disorders

 Delirium

consciousness disturbance, hyperactivity, nocturnal insomnia, sleep-wake cycle disturbance, nightmare

 Panic disorder

panic attacks during NREM sleep

 Posttraumatic stress disorder

insomnia, nightmare

 Psychogenic nonepileptic seizures

epileptic seizure-like symptoms during waking

 Dissociative (conversion) disorders

amnesia, fugue, stupor, motor disorders, convulsion

  1. aAdapted from Breen et al. (2018)