Obstructive sleep apnoea is associated with dynamic intra-thoracic central airway collapse: results of a 10-year multi-centre retrospective analysis

Table 4 Adjusted linear regression models assessing associations between intra-thoracic central airway collapse and obstructive sleep apnoea

OSA index	Confounders in adjusted model	Expected change in OSA index with a 10% increase in dynamic intra-thoracic airway collapse	95% confidence interval	P value
AHI	Gender, BMI	5.4 events/hour	0.9 to 10 events/hour	0.0187
Supine AHI	Gender, BMI	3.8 events/hour	−3.5 to 11.1 events/hour	0.3129
AHI in REM sleep	BMI	−0.5 events/hour	−5.4 to 4.4 events/hour	0.84
RDI	Gender, BMI	5.5 events/hour	0.8 to 10.2 events/hour	0.0230
ODI	Gender, BMI	10.6 events/hour	4.5 to 16.6 events/hour	0.0006
Average SpO2 in supine sleep	BMI	−1.5%	−0.6 to −2.5%	0.001
Average SpO2 in non-supine sleep	FEV1	−1.2%	−0.4 to −2.0%	0.0038

Legend: Associations are described by the expected change in the obstructive sleep apnoea index given a 10% increase in dynamic intra-thoracic central airway collapse. OSA obstructive sleep apnoea, AHI apnoea hypopnoea index, BMI body mass index, REM rapid eye movement sleep, RDI respiratory disturbance index, ODI oxygen 3% desaturation index, SpO2 peripheral oxygen saturation, FEV1 forced expiratory volume in 1 sec

ISSN: 2398-2683