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Table 1 Participant characteristics at baseline according to sleep disturbance

From: Longitudinal associations between sleep disturbance and disease severity in patients with COPD

 

Total

(N = 157)

Sleep disturbance

(n = 74)

No sleep disturbance

(n = 83)

Unadjusted p-value

Age, year, mean (SD)

66.3 (6.4)

66.5 (6.2)

66.1 (6.5)

0.67

Sex, male, n (%)

85 (54.1%)

44 (59.4%)

41 (49.4%)

0.21

White, n (%)

151 (96.2%)

70 (94.6%)

81 (97.5%)

0.33

BMI, mean (SD)

27.6 (4.1)

26.9 (4.0)

28.2 (4.2)

0.04

Pack years, mean (SD)

64.8 (34.1)

66.9 (34.2)

62.9 (34.1)

0.46

Current smoker, n (%)

62 (39.5%)

35 (47.3%)

27 (32.5%)

0.06

Supplemental oxygen use, n (%)

9 (5.7%)

5 (6.8%)

4 (4.8%)

0.60

ICS use, n (%)

8 (5.1%)

6 (8.1%)

2 (2.4%)

0.11

OCS use,a n (%)

40 (25.5%)

20 (27.0%)

20 (24.1%)

0.67

GOLD stage, n (%)

 Stage 1

46 (29.3%)

20 (27.0%)

26 (31.3%)

0.77

 Stage 2

87 (55.4%)

42 (63.5%)

45 (54.2%)

 

 Stage 3

21 (13.4%)

10 (13.5%)

11 (13.3%)

 

 Stage 4

3 (1.9%)

2 (2.7%)

1 (1.2%)

 

GOLD ABCD group, n (%)

 Group A

106 (67.5%)

47 (63.5%)

59 (71.1%0

0.64

 Group B

26 (16.6%)

13 (17.6%)

13 (15.7%0

 

 Group C

14 (8.9%)

7 (9.5%)

7 (8.4%)

 

 Group D

11 (7.0%)

7 (9.5%)

4 (4.8%)

 

Comorbidities, n (%)

 Diabetes

9 (5.7%)

3 (4.2%)

6 (7.2%)

0.42

 Hyperlipidemia

84 (53.5%)

39 (53.4%)

45 (55.6%)

0.79

 Cancer

25 (15.9%)

8 (10.8%)

17 (20.5%)

0.10

 Asthma

17 (10.8%)

30 (40.5%)

20 (24.7%)

0.32

 GERD

50 (31.8%)

10 (13.9%)

7 (8.8%)

0.04

 Bronchitis

75 (47.8%)

42 (60.0%)

33 (42.3%)

0.03

BDI-II category, n (%)

 Minimal/Mild

151 (96.2%)

69 (93.2%)

82 (98.8%)

0.07

 Moderate/ Severe

6 (3.8%)

5 (6.8%)

1 (1.2%)

0.56

 FEV1 pp., mean (SD)

69.3 (18.4)

8.4 (19.0)

70.2 (18.1)

0.40

 mMRC, mean (SD)

1.1 (0.9)

1.1 (1.1)

0.9 (0.9)

0.005

 SGRQ, mean (SD)

25.0 (17.2)

29.0 (18.1)

21.4 (15.6)

0.72

 ISWT distance (m), mean (SD)

399.6 (146.7)

394.9 (141.8)

403.6 (152.0)

0.58

 RV pp., mean (SD)

138.4 (35.9)

140.1 (34.8)

136.8 (37.0)

0.99

 RV/TLC, mean (SD)

0.49 (0.10)

0.49 (0.10)

0.49 (0.10)

0.15

 DLCO pp., mean (SD)

66.9 (19.8)

64.5 (21.6)

69.1 (18.0)

0.56

  1. BDI-II Beck Depression Inventory-II, BMI body mass index, FEV1pp forced expiratory volume in 1 s percent predicted, GERD gastroesophageal reflux disease, SD standard deviation, mMRC modified Medical Research Council scale, SGRQ St. George’s Respiratory Questionnaire, ISWT = Incremental shuttle walk test, RV pp residual capacity percent predicted, DLCO pp diffusion capacity for carbon monoxide percent predicted
  2. aOral steroid use, temporary short-term use in past 6 months