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Table 2 Linear regression analysis with presence of sleep disturbance at baseline as independent variable and COPD severity at baseline as dependent variable

From: Longitudinal associations between sleep disturbance and disease severity in patients with COPD

 Dependent VariableDependent Variable
Baseline FEV1 ppBaseline mMRCBaseline SGRQBaseline ISWT distanceRV ppDLCO pp
β95% CIp-valueβ95% CIp-valueβ95% CIp-valueβ95% CIp-valueβ95% CIp-valueβ95% CIp-value
Model 1:
 Baseline SD−0.05(−7.35, 2.55)0.340.07(− 0.18, 0.45)0.400.22(2.33, 12.97)0.005− 0.03(−56.29, 38.98)0.720.05(−8.17, 14.59)0.57− 0.11(− 10.77, 1.71)0.15
Model 2:
 Baseline SD− 0.04(− 6.34, 2.05)0.320.07(− 0.19, 0.46)0.420.22(2.08, 13.21)0.007− 0.10(− 72.10, 12.12)0.16−0.02(− 12.30, 10.13)0.85− 0.09(− 9.68, 2.49)0.25
 Age0.31(0.82, 1.39)< 0.0010.11(− 0.01, − 0.04)0.17− 0.01(− 0.47, 0.40)0.87− 0.35(− 11.20, −4.68)< 0.001−0.15(− 1.70, 0.05)0.070.02(− 0.41, 0.53)0.80
 Sex0.02(− 3.27, 5.12)0.670.09(− 0.14, 0.50)0.270.07(− 3.20, 7.90)0.40− 0.34(− 140.02, − 56.77)< 0.001− 0.24(− 28.44, − 6.06)0.003−0.09(− 9.67, 2.47)0.24
 Race−0.04(− 15.04, 5.11)0.330.12(− 0.18, 1.51)0.120.06(− 9.34, 19.84)0.48− 0.04(− 136.17, 80.11)0.610.07(− 16.46, 42.30)0.39−0.10(− 25.96, 5.96)0.22
 BMI0.21(0.70, 1.54)< 0.001− 0.07(− 0.06, − 0.03)0.44− 0.03(− 0.82, 0.57)0.72−0.17(− 11.55, − 0.90)0.02−0.21(− 3.19, − 0.38)0.010.34(0.86, 2.38)< 0.001
 Smoking status− 0.40(− 28.39, − 18.82)0.350.10(− 0.14, 0.53)0.240.01(− 5.30, 6.22)0.16− 0.10(− 74.06, 13.69)0.18− 0.13(− 12.34, 10.57)0.90− 0.19(− 13.87, − 1.27)0.02
  1. Note: FEV1 pp. = forced expiratory volume in 1 s percent predicted, mMRC = modified Medical Research Council scale, SGRQ = St. George’s Respiratory Questionnaire, ISWT = Incremental shuttle walk test, β = standardized regression coefficient, 95% CI = 95% confidence interval, SD = sleep disturbance, BMI = body mass index, RV pp. = residual capacity percent predicted, DLCO pp. = diffusion capacity for carbon monoxide percent predicted